last updated on 6 October 2017

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    Wednesday, 11 October 2017

    08:00 Registration and coffee

    09:30 Opening Words

    Session 1: Environmental Exposure Pathways

    Chair: Christoph van Thriel

    • 10:00
      Keynote: “Evaluating the Environmental Health and Safety Implications of Engineered Nanomaterials”
      William K. Boyes, United States Environmental Protection Agency, Washington D.C., USA
    • 10:45
      “Modeled Engineered Nanomaterial (CeO2, SiO2, Ag) Releases and Concentrations in Germany”
      Fadri Gottschalk, Institute of Safety and Risk Sciences (ISR), BOKU, Vienna, Austria
    • 11:05
      Coffee break

    Session 2: Safe by Design

    Chair: Annette Kraegeloh

    • 11:25
      Keynote: “High-Throughput for Toxicology and Material Discovery with Particle Technology”
      Lutz Mädler, Foundation Institute of Materials Science (IWT) and University of Bremen, Germany
    • 12:10
      “The Safe-By-Design Concept and a Corresponding Platform for Nanomaterials, Driven by the Requirements of Regulations and Other Needs”
      Blanca Suárez Merino, TEMAS AG, Zurich, Switzerland
    • 12:30
      “Lab-on-a-Chip-Based High-Throughput Screening of the Engineered Nanomaterial Toxicity”
      Tommy Tong, Monash Institute of Pharmaceutical Sciences, Melbourne, Australia
    • 12:50

    Session 3: Regulatory Issues and Long Term Effects

    Chair: Heinz Fehrenbach

    • 14:00
      “Risk, Regulation and Responsible Innovation”
      Maurice Brennan, University of Birmingham, UK
    • 14:20
      “European Standardization in Nanotechnologies and Relation with International Work. How Standardization Can Help Industry and Regulators in Developing Safe Products?”
      Patrice Conner, AFNOR, La Plaine Saint-Denis, France
    • 14:40
      “NanoValid: Developing Reference Methods for Risk Assessment of Engineered Nanomaterials”
      Rudolf Reuther, NordMiljö AB, Arvika, Sweden
    • 15:00
      “Tuball ™ Single wall Carbon Nanotubes: Health, Safety & Environmental issues”
      Gunther van Kerckhove, OCSiAl Europe Sarl, Luxembourg15:00
    • 15:20
      Coffee break
    • 15:40
      Poster Session 1

    Session 4.1: Quantification and Detection of Nanoobjects

    Chair: Annette Kraegeloh

    • 16:45 – 17:20
      Invited: “Labelled SiO2 Nanoparticles as Markers of Contamination during Nanomaterial Handling Operations”
      Jesús Santamaría, Nanoscience Institute of Aragon, University of Zaragoza, Spain
    • 19:15
      Conference Dinner
      “Luminanz”, Quartier Eurobahnhof, Europaallee 21, 66113 Saarbrücken
    Thursday, 12 October 2017

    Session 4.2: Quantification and Detection of Nanoobjects

    Chair: Eduard Arzt

    • 09:00
      Keynote: “Cryo Electron Tomography: Imaging Cells at the Nanoscale”
      Wolfgang Baumeister, Max Planck Insitute of Biochemistry, Martinsried, Germany
    • 09:45
      “Uptake Monitoring and Quantification of Nanomaterials at Single Cell Level by Means of Element- and Molecule Based Imaging and Dosimetric Techniques”
      Irina Estrela-Lopis, Institute of Medical Physics and Biophysics, University Leipzig, Germany
    • 10:05
      “Ultrasensitive Detection, Quantification and Identification of Engineered and Natural Nanoparticles Using Wide-Field Surface Plasmon Microscopy”
      Vladimir Mirsky, Institute of Biotechnology/Nanobiotechnology, Brandenburg University of Technology, Senftenberg, Germany
    • 10:25
      “Synthesis and Functionalisation of Bright Fluorescent Silica Nanoparticle Probes for High-Resolution STED and Confocal Microscopy”
      Isabella Tavernaro, INM – Leibniz Institute for New Materials, Saarbrücken, Germany
    • 10:45
      Coffee break

    Session 4.3: Quantification and Detection of Nanoobjects

    Chair: Annette Kraegeloh

    • 11:05
      Invited: “Radiolabeling – an Appropriate Tool to Study the Environmental Fate of Engineered Nanoparticles”
      Karsten Franke, Helmholtz-Zentrum Dresden-Rossendorf, Germany
    • 11:40
      “Single Cell Level Quantification of Nanoparticle-Cell Interactions Using Mass Cytometry”
      Angela Ivask, Laboratory of Environmental Toxicology, Nat. Inst. of Chemical Physics and Biophysics, Tallinn, Estonia
    • 12:00
      “Characterization of Unlabeled Nanomaterials in Complex Environments”
      Melinda Bartok, Schaefer Technologie GmbH, Langen, Germany
    • 12:20

    Session 5.1: Neurotoxicity

    Chair: Klaus Unfried

    • 13:20
      Invited: “Air Pollution, Microglia, and the Lung-Brain Axis”
      Michelle L. Block, The Stark Neuroscience Research Institute, Indianapolis, USA
    • 13:55
      “Investigation of Neurotoxic Effects of Manganese Nanoparticles in 3D Neural Microtissue”
      Christoph van Thriel, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
    • 14:15
      “Development of an In Vitro Model of NanoNeurotoxicity Using Human 3D Neural Tissues”
      Luc Stoppini, Hepia/HES-SO, University of Applied Sciences Western Switzerland, Geneva
    • 14:35
      Coffee break

    Session 5.2: Neurotoxicity

    Chair: Christoph van Thriel

    • 14:55
      “A Daily Exposure of Rabbit Dams to Diesel Exhaust Nanoparticles during Gestation Impairs the Brain and Olfactory Dopaminergic Pathways of Offspring”
      Estefania Bernal-Meléndez, University of Lorraine, Vandoeuvre-les-Nancy, France
    • 15:15
      “Effects of Nanoparticles in the 5xFAD Mouse Model of Alzheimer’s Disease”
      Catrin Albrecht, IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany

    Special Session: Communication of Safety and Risks

    • 15:35
      “DaNa2.0 – Reliable Information on Manufactured Nanomaterials”
      Christoph Steinbach, DECHEMA e.V., Frankfurt a.M., Germany
    • 15:55
      Poster Session 2
    • 17:00 – 18:00
      Safe by Design

    Friday, 13 October 2017

    Session 6.1: Nanomaterial Effects and Mechanisms

    Chair: Heinz Fehrenbach

    • 09:00
      invited: “The Effect of Gold Nanoparticles in Asthma Mouse Model”
      Thai Dinh, Universitätsklinikum des Saarlandes, Homburg, Germany
    • 09:35
      “The Impact of CuO and TiO2 Nanoparticles on Gene Expression Following Air-Liquid Interface Exposure”
      Matthias Hufnagel, Karlsruhe Institute of Technology, Karlsruhe, Germany
    • 09:55
      “How the Protein Corona Evolves on a Nanoparticle”
      Giancarlo Franzese, Departament de Física de la Matèria Condensada, Universitat de Barcelona, Spain
    • 10:15
      “Low-Dose Carbon Black Nanoparticles Exposure of the Lung Does Not Aggravate Allergic Airway Inflammation in Mice”
      Heinz Fehrenbach, Priority Area Asthma & Allergy, Research Centre Borstel, Germany
    • 10:35
      Coffee break

    Session 6.2: Nanomaterials: Effects and Mechanisms

    Chair: Klaus Unfried

    • 10:55
      Invited: “Understanding Nanosafety – The Importance of Assay Performance In Vitro”
      Cordula Hirsch, Empa, St. Gallen, Switzerland
    • 11:15
      “Exposure to Nanoparticles Specifically Extends Neutrophilic Life Span: A Toxicologically Relevant Endpoint for Nanoparticle Safety”
      Tamara Hornstein, IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany
    • 11:35
      Workshop presentation and final discussion
      Poster award
      Closing remarks
    • 12:30
      Brown bag lunch
    • 14:00
      INM guided tour (optional, registration on-site)